Leptin Resistance: test and Symptoms


One of the supreme causes of insurmountable medical jargon upon the visit to a physician in a chaotic cholesterol and obesity rates is that one gets to know leptin afresh. One must start early, taking cues, understanding the body, healing it, growing with it and being aware of the changes in it. Leptin resistance test is one of the options to assert or find evidence in, rather than delude on and on!


What is Leptin Resistance Test?


To begin understanding leptin resistance test, one must understand, in order to increase brain’s sensitivity to the rate of leptin, the test is taken for the better analysis. According to medical research and evidence there is no finite way to determine the rate of leptin in the body other than through blood tests and such, but the possibility is positive to determine the levels of leptin-resistance in blood. The test carried out is ELISA test, which determines the count of leptin level in the blood to the exact precision of ng/ml of blood. Women are known to have leptin levels of 3.9 – 30 while men have should have a lower leptin count of 0.5- 12.7. As much as the undefined territory of Leptin in science is, some cases of highly obese people have shown no leptin content whatsoever.


Why Get Tested For Leptin?


The test for leptin resistance level in the blood determines the person’s rate of leptin deficiency or excess to the precision but not all of its effects. The test provides evidence to take the second step relating to any doubts of cholesterol rates and other binge-eating disorders in the body as well. One should consult the doctor, check with the symptoms for high leptin resistance, and do a test thereon.  


How To Get Tested For Leptin?


The test as described above is an ELISA test and has supporting tests such as for lipids, glucose, thyroid panel, insulin/ A1c in order to determine the site, cause and depth of the leptin resistance in a body. Medically, the test is not prescribed for every case of over-weight patients, but solely for seriously obese patients.  Or, in cases of the genetic history of high obesity previously observed. The test is prescribed for people who have high cravings for food or binge-eating par infinity.  


Another test to determine leptin resistance in blood is to check your blood sugar levels after a good fasting for 12 hours. Go to your doctor and take an Ac1 test. You can opt to be pro-active and request aPAI-1 or Plasminogen Activator Inhibitor- 1 test as well. This should requested alongside CRP or C-reactive protein and Homocysteine. This test is taken as PA-1 medically is the production of a fat-cell hormone that is known to increase cardio-vascular disorders and blood clotting. The second test, CRP is tested to ensure the inflammation levels in the body in order to determine the leptin resistance. The last test, Homocysteine is known to cause clotting of the blood and cardio-vascular disorders.   


Another test to do in this condition is microalbumin in urine test, which determines the protein rate in urine and leptin resistance levels. Next, keep a perpetual check on your triglyceride and cholesterol levels. For testosterone levels, men should have lower rates while women claim to have high rate of DHEA-S as well as adrostenedione rates. Check the liver through an ultrasound to detect presence of fat on the liver.  


What Result To Comprehend, When It Arrives?


Decreased levels of leptin indicate the deficiency of leptin in the body while increased levels of leptin indicate heightened leptin resistance.  Additionally, extremely low or high rate of leptin can also indicate a genetic deficiency or leptin resistance.  


Symptoms of High Leptin in blood


a. Check the weight


b. Check your sleep  


c. Check your blood pressure


d. Check your skin for discoloration, stretch marks, tags and other darkening in the armpits to  show the signal of leptin resistance in the body


e. Acne, fertility problems, abnormal menstruation and facial growth of hair


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